![]() ![]() Journal of Medical Toxicology, 9, 155-162. Review article: The clinical and forensic toxicology of Z-drugs. Goldfrank's toxicologic emergencies (Tenth ed.). Quebec, Canada: Centre antipoison du Quebec. Antidotes en toxicologie d'urgence (3rd ed.). Titrate to effect.īailey, B., Blais, R., Gaudreault, P., Gosselin, S., & Laliberte, M. (2009). ![]() If adequate sedation reversal does not occur after an additional 45 seconds, further injections of 0.01 mg/kg ( up to maximum 0.2 mg) may be repeated at 1 minute intervals, as needed up to 4 times: Maximum total dose 0.05 mg/kg or 1 mg, whichever is lower.Ĭonsider IV infusion of 0.1 mg -1 mg/hour. The following data is based on published case reports.Ġ.01 mg/kg (up to maximum of 0.2 mg) over 15 seconds.
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